ABSTRACT
The underground environment is dark and humid, and it is easy to breed pathogenic microorganisms. A lump in the right lung of a coal mine underground transport worker was found druing occupational health examination. CT examination showed that the lump was located in the posterior segment of the upper lobe of the right lung, with point strip calcification, liquefaction necrosis, and proximal bronchial stenosis and occlusion. MRI examination FS-T(2)WI and DWI showed "target sign", annular low signal around the central high signal, and low mixed signal around the periphery, and annular high signal in the isosignal lesions on T(1)WI. Then the pulmonary aspergillus infection was confirmed by pathology.
Subject(s)
Humans , Coal , Miners , Pneumonia , Lung , Aspergillosis , Coal MiningABSTRACT
To observe predictive value of plasma brain natriuretic peptide (BNP) for prognosis in patients with chronic heart failure preserved left ventricular ejection fraction (HFpEF).Methods : A total of 122 CHF pa‐tients from 2014 to 2016 , according to LVEF , patients were divided into LVEF reduced HF (HFrEF ) group (LVEF≤ 40%, n＝ 41) , HF with medium LVEF (HFmEF ) group (40% ＜ LVEF＜ 50%, n＝ 40 ) and HFpEF group (LVEF≥50%, n＝ 41).Clinical data , plasma BNP level etc .were measured and compared among three groups ;ROC was used to analyze cutoff point of plasma BNP predicting short‐term major adverse endpoint (SMAE) in CHF patients .Results : For LVEDd , HFpEF grou P＜ HFmEF group＜ HFrEF group , there existed significant difference between any two groups , P＝0.001 all.Left atrial diameter (LAD) of HFpEF group and HFmEF group were significantly higher than that of HFrEF group , P＜0.05 both .Compared with HFpEF group , there was sig‐nificant rise in plasma BNP level [(789.39 ± 455.62) pg／ml vs.(1143. 40 ± 567.99) pg／ml vs.(2341.51 ± 1029. 99) pg／ml] in HFmEF group and HFrEF group , and that of HFrEF group was significantly higher than that of HFmEF group , P＜0. 01 all.Multifactor Logistic regression indicated that plasma BNP level was independent risk factor for SMAE events in HFmEF and HFrEF patients (OR＝1.006 , 1.001 , P＜0.05 both).ROC analysis indicated that AUC of plasma BNP predicting SMAE in CHF patients was 0.818 , cutoff point was 1415pg／ml , and sensitivity and specificity was 82. 6% and 72. 7% respectively .There was no significant difference in rehospitalization rate and mortality during hospitalization and within 12‐month follow‐up after discharge among three groups , P＝ 0.328. Conclusion : Plasma BNP possesses good predictive value for short‐term rehospitalization and death events in HFmEF and HFrEF patients , but it can′t predict endpoint events of HFpEF patients .